This species is similar to Palicourea crocea and these are often confused, and they can be extremely difficult to separate as herbarium specimens. Palicourea crocea generally has shorter corollas that are usually orange or red, and are darker than the inflorescence axes, which are often yellow. In contrast Palicourea croceoides has larger bright yellow corollas that are lighter in color than the inflorescence axes, which are orange or usually red. Both of these belong to a poorly understood, widespread, morphologically variable complex of species or forms in the Amazon basin including also P. fastigiata. In Puerto Rico individual plants of Palicourea croceoides flower and produce fruits on and off in a generally continual cycle through the year, and the population almost always has at least a few plants in flower.