The genus Homolliella was characterized by its woody habit; interpetiolar triangular stipules; petiolate leaves that are generally pubescent and rather thick-textured; terminal, shortly cymose, rounded, sessile to shortly pedunculate inflorescences; bisexual homostylous flowers; the calyx with a well developed tube and 5 usually rather short lobes; salverform to funnelform, usually externallay sericeous to velutinous corollas with the 5 lobes contorted in bud; the ovary ridged and 2-locular, with 3-4 ovules in each locule; and berry-like fruits with the seeds reniform, somewhat flattened, and with entire endosperm. Only one species has been formally described in this genus.
De Block (2003) noted that this genus is closely related to Paracephaelis and Homollea, although the species of Homollea are not very similar general aspect to the species of these first genera. Homollea differs from these in its generally unbranched inflorescences borne on well developed peduncles and its long narrow calyx lobes. Paracephaelis was separated from Homolliella by in its calyx with the lobes longer than the tube and often shorter flowers, but De Block et al. (2015) based on further study including molecular data were unable to separate these and formally included the single species of Homoliella within Paracephaelis. Also similar to Paracephaelis is Schizenterospermum, but it has the corolla lobes valvate in bud.